Electrochemotherapy (ECT) combines two methods, electroporation and chemotherapy. ECT is used in tumour treatment. Non-permeant or low-permeant active substances with intracellular targets, such as cytotoxic drugs, can be delivered into the interior of the cells via electroporation.
Locally applied intense electric pulses increase the membrane permeability of tumour cells for a short time. Molecules of the applied chemotherapeutic drug can diffuse into the tumour cells and unfold their tumour-destroying effect from the inside.
In Germany this procedure is included in the medical guidelines for treatment of melanoma.
The SENNEX® Medical Device is the medical instrument for ECT Made in Germany.